Human SHP-77 / Luciferase Stable Cells

$3,000.00

SKU: SC085-Luc Categories: ,

Description

SHP-77 cell line is human small cell lung carcinoma (SCLC) epithelial cell line established in 1977. SHP-77 expresses neural cell adhesion molecule (NCAM), NHK-1, CD56, and the cell surface leucocyte antigen Leu-7(HNK-1;CD57). This cell line has a variety of unusual characteristics including the morphology of an undifferentiated large cell variant. It grows as some loosely adherent cells, aggregates in suspension.

SHP-77 Cell line can be used to evaluate the immune status of patients with SCLC who are treated with radiation or chemotherapy. They are suitable for in vitro nude mice assays for evaluation of immune reactivity of cells and serum from lung cancer patients.

Gentarget generated this Luciferase reporter cells,  transformed from human SHP-77 cell line by lentivirus transduction. This cell line expresses the firefly luciferase gene under the enhanced EF1a promoter. It also carries the Puromycin resistance under Rsv promoter. The cell line demonstrates high level of bioluminescence signal via firefly luciferase assay. The following express cassette was integrated into cell line’s genome. 

EF-luc-Puro

Sold at:  1 vial x (2 x 106 cells)/vial, see details in Product Manual.

Cat# SC085-Luc