Description
Pre-packaged rAAV in Serotype-DJ, constitutively express rTta (reverse tetracycline Transcriptional Activator), under a modified enhance EF1a Promoter, No-tag. rTta is used in Tet-On system (when Dox is present, it binds to promoter and turn on the gene expression)
This product expresses a mutant of rtTA (ABC65845.1) that has increased stability and reduced background expression in the absence of the tetracycline or Dox and improved inducibility in the presence of Tet / Dox.
The following scheme showed the AAV vector’s core structure. See Product Manual for details.
AAV Serotype-DJ is a synthetic serotype made from different serotypes using DNA shuffling. AAV-DJ serotype has the enhanced transduction efficiency in vitro and in vivo compared to wild-type serotypes with Broad Cell Tropism, great transduction rate in CNS, Liver, Kidney, Fibroblasts, muscle.
Titer: ~ 1×10^12 GC/mL
Size: 100ul/vial, in stock, ready to ship in overnight Dry-ice package.
Storage Buffer: PBS
CAT#: A4.DJ
