A range of bacterial, viral and protozoal diseases have their infectious antigens that expressed at surface. The infectious antigens are harmful substance that enters the body. They cause the body to make antibodies as a response to fight off disease. Utilizing antigens to raise specific antibody or vaccine is one of the strategies to fight infectious diseases.
Viral genome encodes many proteins to maintain the virus structure and function. The virus surface capsid protein encloses the virus’ genome of DNA or RNA, double-stranded or single-stranded, linear or circular. In some cases, the capsid is surrounds by an envelope protein. The capsid protein and envelope protein determine virus antigenicity. Those proteins on the surface of viruses can activate host’s immunological response, serves as viral antigens.
Lentivirus express infectious antigens:
Gentarget produces lentivirus that express all kinds of infectious antigens. Those expression ready lentivirus can produce high expression in your desired mammalian cell type. Furthermore, you can purify the expressed antigens for raising specific antibodies for vaccine and drug development. The infection antigen expression lentivirus have varieties of application, like,
Used for antigen purification then antibody development
Used for anti-infectious disease tests and screening assays;
Used for validation of antibody’s binding efficiency and assays for vaccine efficiency.
Used for generation of the antigen expression cell line for cell-based assays in antigen detection and validation tests;
Please see each product details in each category below: