Human MP41 / Luciferase & GFP Stable Cells


human MP41 cell line co-express Luciferase and GFP dual report, containing puromycin selection.


Human MP41 cell line was derived from primary Uveal melanoma of 49 years old, female. It forms loose aggregates in culture. Uveal melanoma (UM) is the most common primary tumor of the eye in adults.

MP41 cell line was used as a model in research for the therapeutic option for the treatment of uveal melanoma, and for preclinical validation of mTOR as a therapeutic target

This Luciferase & GFP / human MP41 cell line was transformed via Lentivirus transduction. It has the Luciferase and GFP was constitutively co-expressed under EF1a promoter, as two separate proteins (not as fusion), mediated via 2A element. The Puromycin resistance marker was expressed under Rsv promoter. The following express cassette was integrated into cell-line’s genome. 

GFP and Luciferase co-expression under EF1a promoter

Each cell demonstrates a strong GFP fluorescent signal (see sample image below). Its chem-luminescence signal was verified via luciferase assay using the D-luciferin substrate. And its signal can be detected, in vitro and in vivo.

MP41 cell line co-express Luciferase and GFP dual reporters

Sold at:  1 vial x (2 x 106 cells)/vial, see details in Product Manual.

Cat# SC089-LG