Transformed from HEK293 cells by lentiviral system, this cell line expresses human TRPC3 gene (NM_003305).
TRPC3 was constitutively expressed under an enhanced EF1a promoter. The RFP-Blasticidin marker was expressed under Rsv promoter. The cell constitutively express both TRPC3 and RFP.
The TRPC3 protein is a membrane protein that can form a non-selective channel permeable to calcium and other cations. The encoded protein appears to be induced to form channels by a receptor tyrosine kinase-activated phosphatidylinositol second messenger system and also by depletion of intracellular calcium stores.
Sold at: 1 vial x (2 x 106 cells)/vial, see details in Product Manual.