Human Cytomegalovirus (CMV/HHV-5) Human cytomegalovirus (HCMV), officially known as HHV-5, is a member of the Betaherpesvirinae subfamily of enveloped, linear double-stranded DNA viruses in the family Herpesviridae. The virion envelope is estimated to be 10 nm thick and contains at least 10 abundant protein species.
HHV-5 envelope glycoprotein B (click to see its protein sequence) Viral Like Particles was packaged in HEK293T cells using our proprietary technology. It is the replication-incompetent particles in which the Ebolavirus Envelope (with 6His-tag at its C-terminal) was pseudo-typed as the lentiviral particles’ surface envelope protein. [Note: This VLP has the Ebolavirus Envelope antigen expressed on the particle’s surface. If you want to over-express the Ebolavirus Envelope antigen in your desired cell types, please use lentivirus product, CAT#: LVP1409-PBS.]
This VLP packaged a non-sense sequence (Null) as the particle’s virion genomic material, to maintain the intact of the particles.
HHV-5 envelope glycoprotein B was assembled as surface antigens which can be used as the ready-to-use envelope glycoprotein B antigen, or for raising the specific antibodies, for the validation of anti-envelope glycoprotein B antibodies, in vaccine development and other validation assays. This VLP can also be detected by the anti-C-terminal 6His-tag antibody.
The VLP’s titer was measured via ELISA P24 assay. Every single particle assembled many envelope molecules at its surface. See more details in Product Manual.
Amount: 200ul/vial at 1×108 VP/ml.