Human HCT116 / Luciferase Stable Cells


SKU: SC088-Luc Categories: ,


Human HCT116 cell line is derived from human colorectal carcinoma (Adult male). It has a mutation in codon 13 of the ras proto-oncogene. The cells are adherent with an epithelial morphology. HCT 116 cells are positive for transforming growth factor beta 1 (TGF beta 1) and beta 2 (TGF beta 2) expression.

HCT116 cell line was used in tumorigenicity studies in vitro and in vivo. It forms primary tumor after implantation into nude mice, which makes it a great tool for studying the mechanisms of tumor growth and metastasis.

Gentarget generated this Luciferase reporter cells,  transformed by luciferase lentivirus transduction. This cell line expresses the firefly luciferase gene under the enhanced EF1a promoter. It also carries the Puromycin resistance under Rsv promoter. The cell line demonstrates high level of bioluminescence signal via firefly luciferase assay. The following express cassette was integrated into cell line’s genome. 

Sold at:  1 vial x (2 x 106 cells)/vial, see details in Product Manual.

Cat# SC088-Luc