Stable Cell Line Express COVID-19 S Protein

There are many types of Coronaviruses which are common human pathogens. At early 2020, a novel coronavirus breakout in Wuhan China, and cause the current pandemic. On Feb 11, 2020, WHO named this virus as COVID-19 and the international Committee of Virus Taxonomy named it as SARS-Cov-2.

Research found the COVID-19 bind human ACE2 receptor with high affinity through its Spike (S) protein. Therefore, inhibitor the binding between S protein and ACE2 is the main goal for drug, antibody or vaccine development again COVID-19.

Gentarget developed a stable cell line (CAT#: SC077) express the  full length S-protein spike protein (S protein) of COVID-19 (SARS-CoV-2). This cell line was generated by transform human Hela cell with S protein expression lentivirus (CAT#: LVP1329) containing a C-terminal 6 Hig which can be used for the purification or detection of the express S protein.

The cell line can be used to mimic COVID-19 (SARS-CoV-2) in cell based assays for the COVID-19 detection, vaccine validation, anti-COVID-19 antibody verification, and more.